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新城疫分离株与La Sota疫苗交叉免疫保护性研究
引用本文:王爱华,陈建新,苏杰.新城疫分离株与La Sota疫苗交叉免疫保护性研究[J].河北北方学院学报(自然科学版),2007,23(3):32-34.
作者姓名:王爱华  陈建新  苏杰
作者单位:1. 河北北方学院动物科技学院医学系,河北,张家口,075000
2. 河北北方学院科研处,河北,张家口,075000
基金项目:张家口市科技局资助项目(061151)
摘    要:用新城疫(ND)分离强毒油佐剂灭活苗和NDV La Sota油佐剂灭活苗分别免疫带有新城疫母源抗体的雏鸡,免疫后每7d采集血清,用微量血凝抑制试验方法检测HI抗体.并于免疫后第21、28、35 d用鸡新城疫分离毒和NDV F_(48)E_9分别进行攻毒试验,结果显示,免疫鸡的HI抗体水平没有大的差异,分离毒株灭活苗对鸡新城疫强毒感染的免疫保护效力优于La Sota灭活苗.

关 键 词:新城疫病毒  免疫保护  灭活苗
文章编号:1673-1492(2007)03-0032-03
修稿时间:2007-04-17

A Cross Immunoprophylaxis Experiment with Chicken NDV Isolated Strain and NDV La Sota Vaccine Strain
WANG Ai-hua,CHENG Jian-xin,SU Jie.A Cross Immunoprophylaxis Experiment with Chicken NDV Isolated Strain and NDV La Sota Vaccine Strain[J].Journa of Hebei North University:Natural Science Edition,2007,23(3):32-34.
Authors:WANG Ai-hua  CHENG Jian-xin  SU Jie
Institution:1. Department of Animal Medicine, College of Animal Science, Hebei North University, Zhangjiakou 075000, Hebei, China;2. Office of Scientific Research Administer, Hebei North University, Zhangjiakou 075000, Hebei, China
Abstract:Chicken with NDV antibodiesis was immunized with the oil adjuvant inactivated vaccine NDV Isolated Strain and the oil adjuvant NDV LaSota strains vaccine.After the inoculability,the titres of the serum NDV antibodies were tested by the Micro-HI every 7 d.Immunized chickens were respectively challenged by NDV Isolated Strain and standard F_(48)E_9 in 21th,28th and 35th day after immunization.The results showed that there was no difference between the two inactivated vaccine in immune efficacy.Isola- ted inactivated vaccine provided a better immune protection than La Sota inactivated Vaccine.
Keywords:Newcastle disease virus  immunoprophylaxis  inactivated vaccine
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