| 7-(3-芳基)丙烯酰氧基-4-甲基香豆素的合成 |
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| 引用本文： | 严春临,张季,杨树平.7-(3-芳基)丙烯酰氧基-4-甲基香豆素的合成[J].河北北方学院学报(自然科学版),2007,23(2):17-19,27. |
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| 作者姓名： | 严春临 张季 杨树平 |
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| 作者单位： | 1. 河北北方学院药学系,河北,张家口,075000
2. 内蒙古医学院药物化学教研室,内蒙古,呼和浩特,010059 |
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| 摘 要： | 合成7-(3-芳基)丙烯酰氧基-4-甲基香豆素类化合物.方法:以酰氯法,经酯化反应,制得7种相应香豆素类化合物.结果:结构经元素分析、红外光谱、紫外光谱确定7种化合物(Ⅲa—Ⅲg)未见文献报道.结论:用酰氯法制备7-(3-芳基)丙烯酰氧基-4-甲基香豆素类化合物是简便易行的.
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| 关 键 词： | 香豆素 肉桂酸 药物合成 |
| 文章编号： | 1673-1492（2007）02-0017-03 |
| 修稿时间： | 2006-12-06 |
Synthesis of 7-(3-Aryl) acryloxy-4-methyl Coumarins |
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| YAN Chun-lin,ZHANG ji,YANG Shu-ping.Synthesis of 7-(3-Aryl) acryloxy-4-methyl Coumarins[J].Journa of Hebei North University:Natural Science Edition,2007,23(2):17-19,27. |
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| Authors: | YAN Chun-lin ZHANG ji YANG Shu-ping |
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| Institution: | 1. Department of Pharmacology, Hebei North University, Zhangjiakou 075000, Hebei, China; 2. Department of Medical Chemistry, Innermongolia Medical College, Huhhot 010059, Innermongolia, China |
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| Abstract: | Objective:The purpose is to synthesize 7-(3-Aryl)acryloxy-4-methyl Coumarins.Methods:Compounds were obtained from the reaction of 7-Hydroxy-4-methyl Coumarins with substituted cinnamic acid.Results:A series of 7-(3-Aryl)acryloxy-4-methyl Coumarins were synthesized.Their structures were unreported and unidentified by IR,UV and elemental analysis data.Conclusion:The method of synthesizing 7-(3-Aryl)acryloxy-4-methyl Coumarins is simple,convenient and feasible. |
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| Keywords: | coumarin cinnamic acid drug synthesis |
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