| circRNA的生物学功能及其在家畜动物上的研究进展 |
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| 引用本文： | 李京京,齐晓龙,王相国,邢 凯,常 迪,郭 勇,倪和民,盛熙晖.circRNA的生物学功能及其在家畜动物上的研究进展[J].中国农学通报,2020,36(3):142-146. |
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| 作者姓名： | 李京京 齐晓龙 王相国 邢 凯 常 迪 郭 勇 倪和民 盛熙晖 |
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| 作者单位： | 北京农学院动物科学技术学院,北京 102206 |
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| 基金项目： | 北京市属高等学校高层次人才引进与培养计划项目“circRNA/miR-7 调控猪骨骼肌成肌细胞增殖的机制研究”(CIT&TCD201704050);北 京市科技新星计划“miRNAs 调控猪肌肉发育的机理研究”(No.Z161100004916075);现代农业产业技术体系北京市家禽创新团队(BAIC04-2018)。 |
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| 摘 要： | 环状RNA(circRNA)是一类内源性的环状非编码RNA。目前circRNA的研究主要集中在癌症、肿瘤等方面,在家畜动物中的研究较少且主要集中在circRNA的信息挖掘。本文总结了circRNA的生成方式、分类、研究方法及生物学功能等方面内容,归纳了其在家畜动物肌肉发育、脂肪沉积等方面的研究进展,分析总结了目前家畜动物circRNA研究中存在的问题,并对其未来的研究方向进行了展望。
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| 关 键 词： | circRNA 生成方式 研究方法 生物学功能 家畜动物 |
| 收稿时间： | 2018/9/16 0:00:00 |
| 修稿时间： | 2019/12/20 0:00:00 |
The Biological Function of circRNA and Its Research Progress in Domestic Animals |
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| Li Jingjing,Qi Xiaolong,Wang Xiangguo,Xing Kai,Chang Di,Guo Yong,Ni Hemin,Sheng Xihui.The Biological Function of circRNA and Its Research Progress in Domestic Animals[J].Chinese Agricultural Science Bulletin,2020,36(3):142-146. |
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| Authors: | Li Jingjing Qi Xiaolong Wang Xiangguo Xing Kai Chang Di Guo Yong Ni Hemin Sheng Xihui |
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| Institution: | Animal Science and Technology College, Beijing University of Agriculture, Beijing 102206 |
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| Abstract: | circRNA is a kind of endogenous and circular non-coding RNAs. At present, the researches on circRNA mainly focus on cancer and tumor. There are fewer studies on circRNA in domestic animals, most of which are about the information mining of circRNA. In this paper, the generation way, classification, research methods, biological functions of circRNA are summed up. The research progress of circRNA on muscle development and fat deposition of domestic animals are summarized. Finally, the research problems of circRNAs in domestic animals are analyzed, and the future research direction of circRNA is discusse. |
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| Keywords: | circRNA generation research method biological function domestic animal |
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