环境和食品中阿维菌素类药物残留量检测方法研究进展

阿维菌素类药物是一种常用的杀虫剂,现有报道的食品和环境基质样品中阿维菌素残留分析最为常用的检测仪器为液相色谱-串联质谱。基于此,已建立了一系列的不同样基质中多种阿维菌素类药物残留量的检测方法,本研究除了关注常见的多种阿维菌素残留量的测定方法,也关注了食品和环境样品中单种阿维菌素化合物的专一性检测方法。本研究从阿维菌素在食品和环境领域的应用以及赋存状态、前处理方式（提取和净化方法）、检测方法（液相色谱法、酶联免疫法和液相色谱-串联质谱法）及定量方式和基质干扰等方面,综述了2010—2020年不同检测技术在食品和环境样品基质中阿维菌素类化合物残留分析中的研究与应用进展。最后,综述了多残留量检测方法的局限性,未来的关注点以及对阿维菌素残留分析方法的发展趋势。本研究可为开展烟草中阿维菌素类化合物残留分析技术研究提供参考。

Analytical Methods for the Determination of Avermectins Residues in Food and Environmental Samples: A Review

Avermectins is a kind of frequently used pesticide. The most widely used detection technique for the determination of avermectins residues in food and environmental samples is liquid chromatography coupled to tandem mass spectrometry. Based on this, multi-residue analytical methods with selective sample treatment methodologies in different samples have been developed. This review focuses not only on these common multi-residue methods but also on specific single-residue methods for the analysis of avermectin residues in food and environmental samples. This study summarizes analytical methods in the last decade for the determination of avermectins residues in food and environmental samples, including the applications of avermectin and its occurrence state in food and environmental samples, the sample preparation methods (including extraction and clean methods), analytical methods (including HPLC, ELISA and LC-MS/MS) as well as its quantitation mode and methods to reduce matrix interference. Finally, the limitations of multi-residue methods, the future perspectives and the trends for avermectins residues analysis in food and environmental samples are reviewed. The study will be helpful for future research in the field of determination of avermectins residues in tobacco.