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茶氨酸酶促生物合成研究进展
引用本文:陈林,张正竹,陈键,张应根,宛晓春.茶氨酸酶促生物合成研究进展[J].茶叶科学,2011,31(1):1-10.
作者姓名:陈林  张正竹  陈键  张应根  宛晓春
作者单位:福建省农业科学院茶叶研究所;安徽农业大学教育部茶叶生物化学与生物技术重点实验室;
基金项目:福建省属公益类项目(2009R10030-1); 国家自然科学基金(No.30972400)
摘    要:茶氨酸系茶树(Camellia sinensis)特征性成分,具有放松镇静、增强记忆、保护神经、化疗调节等诸多生理活性.目前发现能催化茶氨酸生物合成的酶有7种,它们分别是茶氨酸合成酶、谷氨酰胺合成酶、γ-谷氨酰甲胺合成酶、谷氨酸合成酶、γ-谷氨酰半胱氨酸合成酶、谷氨酰胺酶和γ-谷氨酰转肽酶.茶氨酸生物合成反应有两种代表...

关 键 词:茶氨酸  生物合成    综述

Review on Enzymatic Biosynthesis of Theanine
CHEN Lin,ZHANG Zheng-zhu,CHEN Jian,ZHANG Ying-gen,WAN Xiao-chun.Review on Enzymatic Biosynthesis of Theanine[J].Journal of Tea Science,2011,31(1):1-10.
Authors:CHEN Lin  ZHANG Zheng-zhu  CHEN Jian  ZHANG Ying-gen  WAN Xiao-chun
Institution:CHEN Lin1,2,ZHANG Zheng-zhu2,CHEN Jian1,ZHANG Ying-gen1,WAN Xiao-chun2 1.Tea Research Institute,Fujian Academy of Agricultural Sciences,Fu'an 355015,China,2.Anhui Agricultural University,Key Laboratory of Tea Biochemistry & Biotechnology,Ministry of Education,Hefei 230036
Abstract:As a characteristic component in tea plant(Camellia sinensis),theanine has many favorable physiological effects,such as promoting relaxation,enhancing memory,neuroprotection,modulation of chemotherapy,etc.So far,seven kinds of enzyme have been discovered by which theanine can be synthesized.They are respectively named as theanine synthetase,glutamine synthetase,γ-glutamylmethylamide synthetase,glutamate synthetase,γ-glutamylcysteine synthetase,glutaminase and γ-glutamyltranspeptidase.The two representative reaction types for theanine biosynthesis are linking reaction between glutamic acid and ethylamine in the presence of ATP and γ-glutamyl transfer reaction in which γ-glutamyl group from hydrolysis of glutamine is transferred to ethylamine.In order to apply and develop the exiting methods for microbial production of theanine,the ways involved in enzymatic synthesis of theanine are systematically summarized in this paper.
Keywords:theanine  biosynthesis  enzyme  review  
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