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茶氨酸对ICR小鼠免疫功能的影响及其急性毒性初步研究
引用本文:谭俊峰,李靓,何普明,吕海鹏,郭丽,林智.茶氨酸对ICR小鼠免疫功能的影响及其急性毒性初步研究[J].茶叶科学,2011,31(1):17-21.
作者姓名:谭俊峰  李靓  何普明  吕海鹏  郭丽  林智
作者单位:中国农业科学院茶叶研究所国家茶产业工程技术研究中心;浙江大学茶学系;
基金项目:国家茶叶产业技术体系(NYCYTX-26); 中央级公益性科研院所基本科研业务费专项(0032009030)
摘    要:以ICR小鼠为模型,对小鼠免疫学指标和急性毒性进行测定.免疫实验表明,茶氨酸对小鼠的免疫器官没有影响,但它能有效提高小鼠的碳廓清能力和显著增加小鼠迟发型超敏反应(Delayed type hypersensitivity,DTH)程度.急性毒性试验表明,茶氨酸对雌雄小鼠经口最大耐受量(MTD)均大于20.0 g/kg,...

关 键 词:茶氨酸  免疫力  急性毒性

Effect of Theanine's Immuno-enhancement and Acute Toxicity Based on ICR Mice
TAN Jun-feng,LI Liang,HE Pu-ming,LV Hai-peng,GUO Li,LIN Zhi.Effect of Theanine''s Immuno-enhancement and Acute Toxicity Based on ICR Mice[J].Journal of Tea Science,2011,31(1):17-21.
Authors:TAN Jun-feng  LI Liang  HE Pu-ming  LV Hai-peng  GUO Li  LIN Zhi
Institution:TAN Jun-feng1,LI Liang1,HE Pu-ming2,LV Hai-peng1,GUO Li1,LIN Zhi1 1.National Tea Industry Technology Developing Center,Tea Research Institute,Chinese Academy of Agricultural Sciences,Hangzhou 310008,China,2.Department of Tea Science,Zhejiang University,Hangzhou 310029
Abstract:The effect of theanine on immuno-enhancement ability was evaluated.Results showed that theanine nearly has no impact on mice immune organs.And theanine could effectively enhance the clearing ability of mice.Theanine could also effectively increase the DTH of mice in DNFB induced tests(all does groups being higher compare with the model does),and especially,the high does increased most.The maximal tolerance dose(MTD) on theanine is more than 20.0 g/kg,which illustrate theanine is non-toxic.
Keywords:theanine  immuno-enhancement  acute toxicity  
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