5种中草药提取物对嗜水气单胞菌的体外抑菌效果(摘要)(英文)

[目的]研究5种中草药提取物对嗜水气单胞菌(Aeromonas hydrophila)的体外抑菌效果。[方法]以鱼类常见病原菌嗜水气单胞菌为供试菌,测定了5种中草药对嗜水气单胞菌的体外抑菌作用,并测定了其中效果较好的中草药的治愈率,确定了其最佳用药剂量。[结果]在相同试验条件下,5种中草药中五倍子(Rhuschinensis Mill)、石榴皮(Punica granatum L.)和诃子(Terminalia chebula Retz)对嗜水气单胞菌有较强的抑菌效果,其中五倍子抑菌效果显著高于其他几种中草药(P0.05)。五倍子治疗由嗜水气单胞菌引起的细菌性败血症的最佳治疗剂量为:0.5mg/ml五倍子药液药浴40min,治愈率为100%。[结论]该研究为鱼类暴发性细菌病的防治提供了科学的用药依据。

Research on Anti-bacterial Effects of 5 Kinds of Chinese Herb Extracts on Ameromonas hydrophila in vitro

[Objective] The aim was to study the anti-bacterial effects of 5 kinds of Chinese herb extracts on Ameromonas hydrophila in vitro. [Method] in vitro anti-bacterial effects of 5 kinds of Chinese herb extracts like Galla Chinensis,Syzygium aromaticum,Salvia miltiorrhiza,Punica granatum L. and Terminalia chebula Retz on Ameromonas hydrophila were studied; furthermore,cure rates of the Chinese herb extracts with better anti-bacterial effects were determined to find out the optimal drug dosage. [Result] Under the same experimental conditions,Galla Chinensis,Punica granatum and Terminalia chebula Retz had relatively strong anti-bacterial effects on Ameromonas hydrophila,among them the anti-bacterial effect of Galla Chinensis was significantly higher than those of the others （P0.05）. The optimal treatment dose of Galla Chinensis treating bacterial septicemia caused by Aeromonas hydrophila was that they were treated with medicated bath for 40 min by 0.5 mg/ml Galla Chinensis extract,and the cure rate was 100%. [Conclusion] The research provides a scientific drug basis for the control and prevention of outbreak bacterial diseases of fish.