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精原干细胞研究进展
引用本文:宋瑞高,姚晓磊,石磊.精原干细胞研究进展[J].中国养羊,2014(5):54-57.
作者姓名:宋瑞高  姚晓磊  石磊
作者单位:山西农业大学动物科技学院,太谷030801
基金项目:山西省青年基金项目(2012021027-6);山西农业大学科技创新基金(201201)
摘    要:精原干细胞(spermatogonial stem cells,SSCs)是各种雄性动物生殖细胞的母细胞,是一群具有自我更新和分化潜能的细胞,并且在雄性个体中精原干细胞与下一代的遗传背景密切相关。因此,精原干细胞在细胞生物学、医学、转基因等领域的研究有着广阔的应用前景。文章根据国内外相关研究进展,对精原干细胞的生物学特性、分离纯化与培养、移植等作一概述。

关 键 词:精原干细胞  生物学特性  分离纯化  移植

Advance in Spermatogonial Stem Cells
Authors:Song Rui-gao  Yao Xiao-lei  Shi Lei
Institution:(College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China )
Abstract:Spermatogonial stem cells are oocytes of male mamals germ cells which not only can maintain the number of themselves but also can differentiate to spermatocyte. Spermatogonial stem cells are also closely related to the genetic background of the next male generation individuals. Therefore, the study of spermatogonial stem cells in the field of cell biology,medicine and transgene has broad application prospects. In this review,biological characteristics,isolation,purification,cultivation and transplantation of spermatogonial stem cells were discussed.
Keywords:spermatogonial stem cells  biological characteristics  isolation  purification  cultivation  transplantation
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