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治疗奶牛乳房炎中药凝胶剂载药量及体外释药性研究
引用本文:杨颗粒,富艳玲,和翀翼,王爽,刘文,王晓旭,贺显晶,武瑞.治疗奶牛乳房炎中药凝胶剂载药量及体外释药性研究[J].黑龙江八一农垦大学学报,2011,23(2):24-26,29.
作者姓名:杨颗粒  富艳玲  和翀翼  王爽  刘文  王晓旭  贺显晶  武瑞
作者单位:黑龙江八一农垦大学动物科技学院,大庆,163319
基金项目:黑龙江省教育厅科学技术研究项目
摘    要:检测防治奶牛乳房炎中药凝胶剂的载药量及体外释药性.采用紫外分光光度法测定制剂载药量;采用转篮法进行处方的体外释药试验,用紫外分光光度法测定累积渗透量.紫外分光光度法测定中药复方凝胶剂载药量为21.52%,RSD为0.9%,中药复方凝胶剂累积释放曲线方程为y=2.923 9 Ln(x)+3.258,r2=0.993.采用...

关 键 词:奶牛乳房炎  中药凝胶剂  载药量  体外释药性

Studies on the Drug-loading and Release Profile of Compound Chinese Traditional Medicine Gel Prescribed for Dairy Cow Mastitis in Vitro
Yang Keli,Fu Yanling,He Chongyi,Wang Shuang,Liu Wen,Wang Xiaoxu,He Xianjing,Wu Rui.Studies on the Drug-loading and Release Profile of Compound Chinese Traditional Medicine Gel Prescribed for Dairy Cow Mastitis in Vitro[J].Journal of Heilongjiang August First Land Reclamation University,2011,23(2):24-26,29.
Authors:Yang Keli  Fu Yanling  He Chongyi  Wang Shuang  Liu Wen  Wang Xiaoxu  He Xianjing  Wu Rui
Institution:(College of Animal Science and Technology,Heilongjiang Bayi Agricultural University,Daqing 163319)
Abstract:To determine and protect the drug-loading and release profile of Compound Chinese Traditional Medicine Gel prescribed for dairy cow mastitis in vitro.The drug-loading of Compound Chinese Traditional Medicine Gel was determined by ultraviolet spectrophotometry.The release behavior of Compound Chinese Traditional Medicine Gel was studied by basket method,the cumulative release amounts of Compound Chinese Traditional Medicine liquid were determined by UV.The loading amounts of Compound Chinese Traditional Medicine Gel determined by ultraviolet spectrophotometry was 21.52%,and RSD was 0.9%.The accumulated release curve equation of Compound Chinese Traditional Medicine Gel is y=2.923 9 Ln(x)+3.258,(r2=0.993).The ultraviolet spectrophotometry method was used to determine the drug-loading and release profile of Compound Chinese Traditional Medicine Gel which is specific and accurate with low quantification limit.
Keywords:dairy cow mastitis  compound chinese traditional medicine Gel  drug-loading  release profile
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