Gastrointestinal activity of Ficus sur |
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| Authors: | O O Kunle A Shittu R N Nasipuri O F Kunle C Wambebe P A Akah |
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| Institution: | a National Institute for Pharmaceutical Research and Development (NIPRD) P.M.B. 21, Abuja, Nigeria;b Department of Pharmacology and Toxicology, University of Nigeria, Nsukka, Nigeria |
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| Abstract: | The gastroprotective effects of some extracts of the dried leaves of Ficus sur in animals were investigated in order to validate the use of the plant in traditional medicine. The water and methanol extracts showed antiulcer activity, the hot water extract being the most effective. These extracts had also spasmolytic effects on the rabbit jejunum. LD50 values ranged from 900 to 1200 mg/kg in mice. These results show that F. sur has potential in the treatment of ulcers. |
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| Keywords: | Ficus sur Antiulcer activity |
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