Phylogenetic and Molecular Characterization of the Equine Influenza Virus A (H3N8) Causing the 1997 and 2004 Outbreaks in Morocco |
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| Authors: | Mohamed Boukharta Nadia Touil Elmostafa El Fahim Meriame Terta Bachir Kissi Chafiqua Loutfi Mehdi El Harrak My Mustapha Ennaji |
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| Institution: | 1. Laboratory of Virology, Microbiology, and Quality/ETB, Faculty of Sciences and Techniques, Mohammedia, University Hassan II Mohammadia-Casablanca, Morocco;2. Department of Biology, Instruction Military Hospital Med V Rabat, University Mohammed V Souissi, Rabat, Morocco;3. Functional Genomics Platform, Technical Support Unit for Scientific Research, CNRST, Rabat, Morocco;4. Society of Pharmaceutical and Veterinary Products, Virology Laboratory, Rabat, Morocco |
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| Abstract: | Reported here are the results of antigenic and genetic characterization of equine influenza strains causing local outbreaks reported in Morocco, respectively, in 1997 and 2004. The antigenic and genetic characterizations of the equine influenza virus H3N8 are reported here. The highest similarity between the HA1 nucleotide sequences of A/equine/Nador/1/1997 and those of A/equine/Rome/5/1991 and A/equine/Italy/1199/1992 demonstrate that A/equine/Nador/1/1997 belongs to the European lineage. On the other hand, A/equine/Essaouira/2/2004 and A/equine/Essaouira/3/2004 were classified in the predivergent lineage. The present work emphasizes the importance of a national influenza survey program, which requires a collaborative laboratory network to promote the collection and characterization (antigenic and genetic) of equine influenza viruses in real time. |
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| Keywords: | Equine influenza virus A/equine/Nador/1/1997 A/equine/Essaouira/2/2004 A/equine/Essaouira/3/2004 Predivergent lineage circulation Morocco |
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