| 鸡胚成纤维细胞感染IBDV后SOD活性的变化 |
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| 引用本文： | 薛春宜,毕英佐,曹永长. 鸡胚成纤维细胞感染IBDV后SOD活性的变化[J]. 中国兽医杂志, 1999, 25(1): 3-5 |
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| 作者姓名： | 薛春宜 毕英佐 曹永长 |
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| 作者单位： | 华南农业大学动物科学系,广东广州,510642 |
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| 摘 要： | 鸡胚成纤维细胞用传染性囊病病毒感染后，采用邻苯三酚自氧化法测定细胞超氧化物歧化酶的活性。ＣＥＦｓ感染ＩＢＤＶ后８ｈ，细胞ＳＯＤ活性有所上升。之后，随着时间的延长，细胞ＳＯＤ活性逐渐下降。试验结果表明，ＳＯＤ活性降低是ＣＥＦｓ感染ＩＢＤＶ之后发生的重要生化变化，在ＩＢＤＶ诱导细胞凋亡的过程中可能起关键作用。
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| 关 键 词： | 传染性囊病病毒 鸡胚成纤维细胞 SOD |
| 修稿时间： | 1998-05-27 |
The Changes of SOD Activity in the CEFs Infected with IBDV |
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| Xue Chunyi,Bi Yingzuo,Cao Yongchang. The Changes of SOD Activity in the CEFs Infected with IBDV[J]. Chinese Journal of Veterinary Medicine, 1999, 25(1): 3-5 |
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| Authors: | Xue Chunyi Bi Yingzuo Cao Yongchang |
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| Abstract: | After the Chicken embryo fibroblasts(CEFs) were infected with infectious bursal disease virus(IBDV),the cellular superoxide dismutase (SOD) activity was determined by pargallol autoxidation.Following IBDV infection,the SOD activity of the CEFs increased up to 8h postinfection and decreasd thereafter.These results demonstrate that the decrease in cellular SOD activity is an importand biochemcial change in CEFs infected with IBDV,and may play and crucial role in the process of apoptosis induced by IBDV. |
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| Keywords: | Infectious bursal disease virus Chicken embryo fibroblasts Superoxide dismutase |
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