口服补液盐的临床应用与动物实验研究

作者于1983年开始将以葡萄糖—钠泵学说为理论的口服补液盐(ORS)技术引入我国畜牧兽医领域,经过几年的临床研究;先后在防治犊牛、猪、雏鸡和犬的腹泻脱水等获得86～98.7％的成功率。健康绵羊ORS液吸收实验和与静脉输液、口服蒸溜水吸收比较实验证明,ORS液的各种成分在服后2小时内,不仅能被胃肠粘膜吸收,极显著改善红细胞压积(P<0.01),而且初步观察到促水分吸收的葡萄糖—钠泵现象。

STUDY ON THE CLINICAL APPLICATION AND ANIMAL EXPERIMENTS WITH ORAL REHYDRATION SOLUTION

In 1983, the authors began to study the oral rehydration solution (ORS) which is based on the theory of glucose-sodium pump to control diarrhea and dehydration of calves, pigs, chickens and dogs, and the rate of effectivity was 86-98.7%. Through the absorptive experiments in sheep, ORS was proved to be the best among ORS, Saline-glucose infusion and distilled water. After administration, not only the components of ORS wereable to be absorded by the gastrointestinal mucosa within 2 hours, but PCV was significantly improved (p<0.01).The phenomenon of glucose-sodium pump which promotes the absorption of water was preliminarily observed too.