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| Wnt10b参与外源褪黑激素促进绒山羊绒毛生长的研究 | |
| 引用本文： | 丽春,张文广,常子丽,杨文柱,张燕军,苏蕊,李金泉. Wnt10b参与外源褪黑激素促进绒山羊绒毛生长的研究[J]. 中国畜牧杂志, 2012, 48(7): 5-8 |
| 作者姓名： | 丽春 张文广 常子丽 杨文柱 张燕军 苏蕊 李金泉 |
| 作者单位： | 1. 内蒙古自治区动物遗传育种与繁殖重点实验室,内蒙古呼和浩特010018;内蒙古农业大学动物科学学院,内蒙古呼和浩特010018;加拿大农业食品部,阿尔伯塔列桥T1J4B1 2. 内蒙古自治区动物遗传育种与繁殖重点实验室,内蒙古呼和浩特010018;内蒙古农业大学动物科学学院,内蒙古呼和浩特010018 3. 加拿大农业食品部,阿尔伯塔列桥T1J4B1 |
| 基金项目： | 现代农业产业技术体系建设专项资金资助(ZARS-40-05);内蒙古农业大学博士科研启动基金(206076);内蒙古自然科学基金项目(202140) |
| 摘 要： | 本实验旨在研究Wnt10b在内蒙古成年绒山羊皮肤中的表达变化规律和褪黑激素(MT)对其表达量的影响。每隔1个月按照2 mg/kg BW的剂量在受试内蒙古成年绒山羊耳后皮下埋植MT。连续采集12个月(从2009年8月到2010年7月)的肩胛部皮肤样品,应用实时荧光定量PCR技术检测Wnt10b的表达量。结果表明:Wnt10b在内蒙古成年绒山羊皮肤组织中毛囊生长中期和休止前期高表达;埋植MT提高了Wnt10b在内蒙古成年绒山羊皮肤组织中毛囊休止期和退行期的表达量。结果提示,Wnt10b参与内蒙古绒山羊毛囊生长的信号传递过程,并在退行期和休止期转变过程中发挥作用;Wnt10b参与了外源MT促绒毛生长的毛囊周期性变化过程。 |
| 关 键 词： | 褪黑激素 Wnt10b 绒山羊 |
The Study on Wnt10b Involvement in the Implanting Melatonin Promoting Cashmere Goat Hair Growth |
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| LI Chun , ZHANG Wen-guang , CHANG Zi-li , YANG Wen-zhu , ZHANG Yan-jun , SU Rui , LI Jin-quan. The Study on Wnt10b Involvement in the Implanting Melatonin Promoting Cashmere Goat Hair Growth[J]. Chinese Journal of Animal Science, 2012, 48(7): 5-8 | |
| Authors: | LI Chun ZHANG Wen-guang CHANG Zi-li YANG Wen-zhu ZHANG Yan-jun SU Rui LI Jin-quan |
| Affiliation: | 1,2(1.Key Laboratory of Animal Genetics,Breeding and Reproduction of Inner Mongolia Autonomous Region,Inner Mongolia Hohhot 010018,China;2.College of animal science,Inner Mongolia agricultural University,Inner Mongolia Hohhot 010018,China;3.Agriculture and Agri-Food Canada,Alberta Lethbridge T1J 4B1) |
| Abstract: | This study aims to study the expression levels of Wnt10b in hair follicles of Inner Mongolia Cashmere Goat and the influence of melatonin(MT) on its expression.The MT in dose of 2 mg/kg was implanted behind ears per 2 months during the implanting process.The shoulder skins were collected in 12 months(from August 2009 to July 2010),and Wnt10b expression was detected using qRT-PCR.Wnt10b was strongly expressed in the mature Cashmere goat skin at the middle anagen and catagen phase.The result showed that the expression of Wnt10b increased during telogen and catagen phase in the skin after MT implanting.In conclusion,Wnt10b was involved in the process of signal transmission for hair follicle growth and played the role in the process of transiting from talogen to catagen phase.In addition,Wnt10b was involved in the process of hair follicle cycle growth by implanting MT which promoted Cashmere goat hair growth. |
| Keywords: | melatonin Wnt10b cashmere goat |
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