Case report of a guinea pig (Cavia porcellus) with a surgically treated insulinoma |
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| Affiliation: | 1. Centro Veterinario Madrid Exóticos, Madrid, Spain;2. Town & Country Veterinary Group, Aberdeen, Scotland;1. Institute of Veterinary Pathology, Freie Universitaet Berlin, Berlin, Germany;2. Small Animal Clinic, Freie Universitaet Berlin, Berlin, Germany;1. Department of College of Veterinary Medicine, Kansas State University, 1700 Denison Ave, Manhattan, KS 66502, USA;2. Clinical Sciences and College of Veterinary Medicine, Kansas State University, 1700 Denison Ave, Manhattan, KS 66502, USA;3. Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, 1700 Denison Ave, Manhattan, KS 66502, USA;1. FauneVET, Nantes, France;2. Clinique Vétérinaire des Rochettes, Montaigu, France;3. Centre Hospitalier Vétérinaire Atlantia, Nantes, France;1. Avian & Exotic Animal Clinic, Indianapolis IN, USA;2. Eiken Chemical Co., Taito-ku, Tokyo, Japan;3. Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, FL, USA;4. Division of Comparative Pathology, Department of Pathology, University of Miami Miller School of Medicine, Miami, FL, USA;1. Institute of Veterinary Pathology, Freie Universitaet Berlin, Berlin, Germany;2. Small Animal Clinic, Freie Universitaet Berlin, Berlin, Germany;1. Veterinary Clinic Dr. Bo and Genocchi, Medicina, Bologna, Italy;2. Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell''Emilia, Bologna, Italy |
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| Abstract: | Background: Insulinomas in guinea pigs are poorly documented. Case description: A 2.5-year-old female guinea pig presented with severe hypoglycemia, head tilt, weakness, weight loss, hypothermia and a radiodense abdominal structure. The serum insulin concentration was measured with unsatisfactory results. The animal was treated for acute hypoglycemia with clinical stabilization, prednisolone, diazoxide, and frequent syringe feeding, but severe hypoglycemia recurred and an exploratory laparotomy was performed. Two pancreatic masses were located and removed. The excised tissue was histologically diagnosed as insulinoma with osseous metaplasia. Four months postsurgery the same clinical signs and hypoglycemia recurred. Previous medical treatment was prescribed; however, 20 days later the animal worsened and euthanasia was elected. Conclusions and case relevance: Nodulectomy of an insulinoma in a guinea pig can achieve temporal remission of clinical signs. In guinea pigs with insulinoma head tilt may occur frequently, X-rays may be helpful in revealing a pancreatic mass, and treatment with prednisolone and diazoxide could help in disease management. |
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