The protective effect of pretreatment with killed Corynebacterium parvum against acute babesiosis in calves |
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| Authors: | D.E. Corrier G.G. Wagner |
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| Affiliation: | 1. Department of Veterinary Pathology, USA;2. Department of Veterinary Microbiology and Parasitology, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843, U.S.A. |
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| Abstract: | Yearling calves were pre-treated intravenously (IV) with a 0.20 mg kg?1 dose of Corynebacterium parvum and challenged after 30 days by IV inoculation of 3 × 109Babesia bigemina. The relatively low 0.20 mg kg?1 dose of C. parvum enhanced resistance as indicated by lower mean Babesia parasitemias and less severe decreases in packed-cell volumes than in non-treated calves, but failed to stimulate a significant (P ≤ 0.05) level of protection against B. bigemina challenge. |
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