人工诱发鸡骨质石化病（骨型白血病）及其放射学研究

本文在国内首次报告用骨质石化病患鸡血液腹腔接种１日龄雏鸡，诱发本病获得成功。经Ｘ线摄片检查至２２４日龄止，检出发病率为７４．４％（２９／３９），其中临床型占４４．８％（１３／２９）；隐性型占５５．２％（１６／２９）。公，母鸡的发率分别为８９．５％（１７／１９）和６０％根据（１２／２０）Ｘ线表现和病变程度分为四种类型：１胫骨局限性骨质增生硬化；２．四肢长骨骨质增生硬化与梭状畸形；３．合并局部丘状骨膜

STUDIES ON EXPERIMENTALLY-INDUCED AVIAN OSTEOPETROSIS (OSTEOPATHIC LEUKOSIS)ANDITS RADIOLOGY

This is the first report that avian osteopetrosis could be transmitted successfully byintraperitoneal injection of whole blood into day-old chickens in China. Twenty nineexperimentally induced case:of the disease were diagnosed and studied by radiographyin chickens up to 224 days old. Total incidence was 74.4%(29/39).The birds showingclinical signs amounted to 44.8%(13/29)and occult cases to 55.2%(16 /19).The inci-phic signs and lesions of the disease might be divided into the following four types: (a)localized hyperosteogeny and osteosclerosis in tibia; (b) hyperosteogeny and osteosclerosisand fusiform deformity of tbe long bones in the extremities; (c)combined localizedPeriostosis and osteosclerosis producing protuberances; (d)small focal hyperosteogeny andosteosclerosis in tibia. After carefully studying and comparing the radiographs and secti-ons of bones affected, it was found that most of the lesions of occult cases were locali-zed mainly in the endosteum and compact bones around it,and in the marrow cavity.The routine hematological tests only showed anaemia to varying degree in birds affected,ivhich might be of no much significance in diagnosis of tbe disease- The increased serumalkaline Phosphatase (SAKP) level might reflect the presence of advanced cases.