Ateliotic Dwarfism in the German Shepherd Dog: LOW SOMATOMEDIN ACTIVITY ASSOCIATED WITH APPARENTLY NORMAL PITUITARY FUNCTION (2 CASES) AND WITH PAN-ADENOPITUITARY DYSFUNCTION (1 CASE) |
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| Authors: | Tata Ringberg Lund-Larsen,Jorunn Grø ndalen |
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| Affiliation: | 14.Department of Physiology and the Department of Surgery, Veterinary College of Norway, Oslo, Norway ;24.Department of Physiology, Veterinary College of Norway, P.O.Box 8146, Oslo Dep., Oslo 1, Norway |
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| Abstract: | Two types of ateliotic dwarfism in 3 German Shepherd dog puppies are described. Low somatomedin levels in serum and impaired growth of skeletal tissues were found in all 3 cases.One dog (case 2) had a histologically undeveloped adenohypophysis, and the dwarfism was apparently due to a generalized lack of adenopituitary function.The 2 other dogs (cases 1A and IB) had histologically normal adenohypophyses, and their condition was probably due to a reduced response to endogenous growth hormone in peripheral tissues. |
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| Keywords: | ateliotic dwarfism German Shepherd dog growth hormone somatomedin skeletal growth |
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