Study on Length Polymorphism of KAP1 Family Genes in Yak (Bos gurnniens) |
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| Authors: | SARNAI Arlud E Guang-xin WANG Chen HAN Jian-lin |
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| Institution: | 1. Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
2. Department of Psychosomatic Medicine, Inner Mongolia International Mongolian Hospital, Hohhot 010010, China;
3. Southwest University, Chongqing 400416, China;
4. Sun Yat-sen University, Guangzhou 510006, China |
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| Abstract: | This study was aimed to understand the characteristics of length polymorphism with repeat sequence of keratin associated protein 1 (KAP1) family genes in yak. KAP1 family genes of yak and cattle were sequenced, and compared with sheep KAP1 family gene sequences. The results showed that cattle KAP1 family genes were located in chromosome 19, according to location of sheep KAP1 family genes in the chromosome and similarity with cattle KAP1 family genes, renaming the cattle KAP1 family (according to the gene location of chromosome) B2D, B2A, KAP1-1 and B2C genes into KAP1-4, KAP1-1, KAP1-2 and KAP1-3 gene, respectively. KAP1 family genes in the 3'and 5' flank were highly conserved, the difference between family genes mainly in the the repeat sequence region, which yak KAP1 to KAP4 genes were found 30 bp length polymorphism. There were B(CCQTS)A1(CCQPT) repeat sequence and a new repeat sequence C(SIQTS). The results indicated that the repeat sequence was the key of the polymorphism of KAP1 family genes, which might be relate to combination with keratin protein. |
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| Keywords: | KAP1 family genes yak length polymorphism repeat sequence |
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