突变基因的积累与生殖隔离形成的一个途径（英文）

通过用RR、Rr和rr3种基因型的适合度之比量化R与r基因在后代中的频率,计算r的频率逐代演变的分岔点,研究随机交配群体中的杂合子适合度低于纯合子适合度的突变基因r在群体中的逐代积累过程。揭示了R与r在遗传中的不相容性;遗传漂变能使r在新群体中有较高的频率,超过分岔点,最终形成生殖隔离;同时生物进化的动力仅有突变、遗传漂变、自然选择这3个条件还不够,还需要有杂合子适合度低于纯合子适合度的突变基因,即原有群体的遗传背景对新突变的排斥作用。

Accumulation of Mutant Genes and Its Pathway with Reproductive Isolation

According to the fitness of heterozygote was lower than homozygote among panmictic population,the process of generational accumulate of mutant gene r was considered.Branch point of r＇s frequency by generational evolution which revealed the hereditary incompatibility between R and r,was worked out,and it was found that genetic drift can make r have higher frequency to surpass the branch point to form reproductive isolation.It was not enough to have the three conditions of mutation,genetic drift and natural selection to be the drive of biological evolution;hybrid weakness,the repelling interaction between the genetic background of original population and the new mutation,were also needed.