Programming DNA tube circumferences |
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| Authors: | Yin Peng Hariadi Rizal F Sahu Sudheer Choi Harry M T Park Sung Ha Labean Thomas H Reif John H |
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| Institution: | Department of Computer Science, California Institute of Technology, Pasadena, CA 91125, USA. py@caltech.edu |
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| Abstract: | Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices. |
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