Actinomycin D for Reinduction of Remission in Dogs With Resistant Lymphoma |
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| Authors: | Anthony S. Moore BVSc MVSc Gregory K. Ogilvie David M. Vail |
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| Affiliation: | Department of Medicine, Tufts University School of Veterinary Medicine, North Grafton, MA;Comparative Oncology Unit, Colorado State University School of Veterinary Medicine, Fort Collins, CO;University of Wisconsin-Madison School of Veterinary Medicine, Madison, WI |
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| Abstract: | Twenty-five dogs with malignant lymphoma refractory to chemotherapy were treated with actinomycin D at a median dose of 0.7 mg/m2 (range, 0.5 to 0.9 mg/m2) every 3 weeks. The dogs treated had received between 2 and 8 chemotherapeutic agents (median 7), for a median of 266 days before being treated with actinomycin D. For 23 of the 25 dogs, previous chemotherapy included doxorubicin. No dog responded to actinomycin D chemotherapy. |
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