| 抗肝片吸虫新药碘醚柳胺的合成研究 |
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| 引用本文： | 戴国华,张万义,郭凤兰,贺尊诗.抗肝片吸虫新药碘醚柳胺的合成研究[J].中国兽医学报,1989(1). |
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| 作者姓名： | 戴国华 张万义 郭凤兰 贺尊诗 |
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| 作者单位： | 兽医大学中心实验室
(戴国华，张万义)，兽医大学兽药厂
(郭凤兰)，长春应化所(贺尊诗) |
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| 摘 要： | 以邻二氯苯为起始原料,经硝比、醚化、还原、卤化、缩会等五步反应(总收率约46％),合成了抗肝片吸虫新药碘醚柳胺,并以红外光谱、质谱和元素分析等对此化学结构进行了确证。
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| 关 键 词： | 碘醚柳胺合成 红外光谱分析 质谱分析 元素分析 |
Synthesis of a New Anti-fascioliasis Drug-Rafoxanide |
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| Dai Guohua The Central Laboratory,Veterinary College of PLA.Synthesis of a New Anti-fascioliasis Drug-Rafoxanide[J].Chinese Journal of Veterinary Science,1989(1). |
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| Authors: | Dai Guohua The Central Laboratory Veterinary College of PLA |
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| Abstract: | Rafoxanide or Flukanide, the new anti-fascioliasisdrug, was firstly sythesised in our country from 1, 2-dicholobenzenevia nitration, etherification, reduction, halogenation and condensa-tion steps, the overall yield was about 46%. The structure wasproven by IR, MS and elementary analysis. |
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| Keywords: | synthesis of Rafoxanide IR MS elementary analysis |
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