| 大肠杆菌MM—3基因工程活菌苗免疫母猪所产仔猪抗K_(88ac)及抗LTB抗体动态 |
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| 引用本文： | 娄淑杰,张远钰,王水琴,姜震,陈添弥,黄翠芬.大肠杆菌MM—3基因工程活菌苗免疫母猪所产仔猪抗K_(88ac)及抗LTB抗体动态[J].中国兽医学报,1991(4). |
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| 作者姓名： | 娄淑杰 张远钰 王水琴 姜震 陈添弥 黄翠芬 |
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| 作者单位： | 兽医大学病理教研室
(娄淑杰，张远钰，王水琴)，大庆石油二厂机械化猪场
(姜震)，军事医学科学院生物工程所
(陈添弥)，军事医学科学院生物工程所(黄翠芬) |
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| 摘 要： | 应用BA-ELISA,分别检测了用大肠杆菌MM-3基因工程活菌苗免疫妊娠92d母猪所产仔猪血清和消化液中抗K_(88ac)及抗LTB抗体的动态消长.结果表明,新生仔猪在吃初乳后24h内,血清及消化液中抗K_(88ac)及抗LTB抗体水平均很高,但以后逐渐下降,1周后IgM、2～3周后IgA、3～4周后IgG分别下降到最低水平;仔猪35日龄时,抗体水平有所回升.消化液中抗体水平比血清中抗体水平下降快,并与母体乳汁中的抗体水平呈正相关关系.
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| 关 键 词： | 大肠杆菌基因工程活菌苗 K_(88ac)抗体 LTB抗体 BA—ELISA 仔猪 |
The Kinetic Changes of Antibodies against K_88ac and LTB of En- terotoxigenic E. coli in Serum and Digestive Juice of the Piglets Borne by the Sows Inoculated with MM-3 Genetic Engeneering Live Vaccine |
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| Lou Shujie et al.The Kinetic Changes of Antibodies against K_88ac and LTB of En- terotoxigenic E. coli in Serum and Digestive Juice of the Piglets Borne by the Sows Inoculated with MM-3 Genetic Engeneering Live Vaccine[J].Chinese Journal of Veterinary Science,1991(4). |
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| Authors: | Lou Shujie |
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| Abstract: | BA-ELISA was employed to examine the kinetics of antibodies against K88ac and LTB of enterotoxigenic E. coli in serum and digestive juice of suckling piglets borne by the sowswhich have been inoculated with MM-3 genetic engineering live vaccine at 92 days of the pregnant period. The results showed that the liters of these specific antibodies reached to the peak during the first 24-hours period after sucking colostrum, then declined gradually. The lowest levels of IgM, IgA and IgG occurred at 7-4, 14-21 and 20-30 days of age respectively. The antibody levels in the digestive juice declined more rapidly than the serum antibody levels. |
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| Keywords: | MM-3 genetic engineering live vaccine piglet anti-K88ac antibody anti-LTB antibody BA -ELISA |
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