| 比格犬埃立克体病实验模型的建立 |
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| 引用本文： | 马玉海,潘华,佟世德,孙洋.比格犬埃立克体病实验模型的建立[J].动物医学进展,2001,22(3):52-54. |
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| 作者姓名： | 马玉海 潘华 佟世德 孙洋 |
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| 作者单位： | 广州军区军事医学研究所, |
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| 基金项目： | 全军“九五”医学科研规划课题 (98M0 3 5) |
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| 摘 要： | 为犬埃立克体病的病理学、临床学、病原学的深入研究，我们用Beagle(比格犬）复制犬埃立克体病以建立犬埃立克体病实验模型。比格犬静脉接种E.platy和E.canis后，利用PCR和电镜技术确证感染成功。进一步的观察发现，接种后比格犬与最最感的德国牧羊犬自然感染埃立克体病的临床症关放病理学变化基本吻合。结果说明通过静脉接种病原成功建立了比格犬埃立克体病实验模型。
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| 关 键 词： | 静脉接种病原 比格犬 埃立克体病 实验模型 |
| 文章编号： | 1007-5038(2001)03-0052-03 |
| 修稿时间： | 2001年1月5日 |
The establishment of laboratory model of canine ehrlichiosis in beagles |
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| MA Yu hai,PAN Hua,TONG Shi de,SUN Yang.The establishment of laboratory model of canine ehrlichiosis in beagles[J].Progress In Veterinary Medicine,2001,22(3):52-54. |
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| Authors: | MA Yu hai PAN Hua TONG Shi de SUN Yang |
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| Abstract: | Objective to establish laboratory model of Canine Ehrlichiosis in Beagles, five Beagles that had been artificially infected with Ehrlichia were examined. The infection was proved to be positive for E.canis and E.platys by PCR and electron microscopy. Results showed the artificial infected Beagles were very similar to natural infected German shepherds in clinical manifestation and pathological changes. Therefore, a new laboratory model of Canine Ehrlichiosis was successfully developed in Beagles inoculated with E.canis and E.platys. |
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| Keywords: | beagle canine ehrlichiosis laboratory model |
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