|
|||||
|
|
| 水泡性口炎病毒人工感染小白鼠的组织学和免疫组织化学观察 | |
| 引用本文： | 褚秀玲,苏建青,史秋梅,董国英,高丰.水泡性口炎病毒人工感染小白鼠的组织学和免疫组织化学观察[J].畜牧兽医学报,2005,36(8):855-857. |
| 作者姓名： | 褚秀玲 苏建青 史秋梅 董国英 高丰 |
| 作者单位： | 1. 吉林大学畜牧兽医学院,长春,130062;河北北方学院动医系,张家口,075131 2. 河北北方学院动医系,张家口,075131 3. 河北科技师范学院动科系,昌黎,066600 4. 辽宁省动物防疫站,沈阳,110161 5. 吉林大学畜牧兽医学院,长春,130062 |
| 基金项目： | 国家自然科学基金（30270994） |
| 摘 要： | 水泡性口炎病毒（VSV）具有广泛的宿主范围，临床血清学调查发现，许多动物表现为血清阳性1]，可以感染多种试验动物和禽类。感染动物大多数表现为阴性感染和持续性感染，本试验以小白鼠为攻毒对象，探讨VSV在体内的致病作用，进一步了解病毒在机体内的分布及其所引起的组织病理学变化。 |
| 关 键 词： | 水泡性口炎病毒 组织学 免疫组织化学 |
| 文章编号： | 0366-6964（2005）08-0855-03 |
| 收稿时间： | 2004-11-25 |
| 修稿时间： | 2004-11-25 |
Histopathology and Immunohistochemistry Studies on Mouse Infected by VSV |
|
| CHU Xiu-ling,SU Jian-qing,SHI Qiu-mei,DONG Guo-ying,GAO Feng.Histopathology and Immunohistochemistry Studies on Mouse Infected by VSV[J].Acta Veterinaria et Zootechnica Sinica,2005,36(8):855-857. | |
| Authors: | CHU Xiu-ling SU Jian-qing SHI Qiu-mei DONG Guo-ying GAO Feng |
| Abstract: | Brain, spinal cord, lung, heart and liver of mouse infected by VSV was studied using immunohistochemistry method and HE staining. The results showed that VSV can infect mouse, in earlier period of infection, lesions located mainly in lung, in anaphase of infection, lesions located mainly in brain and spinal cord. Positive cells were found in lung, brain and spinal cord. The positive rate in brain was higher. Results showed that duplication of VSV occured mainly in lung and brain,and cause corresponding pathogenicity. |
| Keywords: | vesicular stomatitis virus histopathology immunohistochemistry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |