CO2激光加得宝松封包治疗肢端型白癜风的疗效观察

目的 观察CO₂激光加得宝松封包治疗肢端型白癜风的临床疗效，为肢端型白癜风寻找新的治疗方法。方法 62例肢端型白癜风患者随机分为观察组和对照组各31例。观察组给予CO₂激光联合得宝松封包；对照组给予梅花针配合得宝松外搽治疗肢端型白癜风。分别观察两组治疗3个月和6个月后的临床疗效，并于治疗结束6个月后随访其复发率。结果 治疗3个月后，观察组有效率54.8%，对照组有效率41.9%，两组之间疗效差异无统计学意义（P>0.05）；治疗6个月后，观察组有效率77.4%，对照组有效率51.6%，两组比较疗效差异有统计学意义（P<0.05），两组患者均无明显不良反应；在治疗结束6个月后观察组复发率16.7%，对照组为50.0%，两组之间复发率差异有统计学意义（P<0.05）。结论 CO₂激光加得宝松封包治疗肢端型白癜风的长期疗效明显优于梅花针配合得宝松外搽治疗，复发率低，安全性有保障。

Clinical Observation of CO2 Laser combined with Debaosong Packet in the Treatment of Acral Vitiligo

Objective To observe the clinical treatment efficacy of CO₂ laser combined with Debaosong packet on acral vitiligo, and find a new treatment method for the acral vitiligo. Methods 62 acral vitiligo patients were randomly divided into the observation group and control group, 31 cases in each group. The patients in the observation group was treated with CO₂ laser combined with Debaosong packet, and the control group was treated with plum blossom needle combined with external application of Debaosong. The efficacy for the two groups were observed at 3-month and 6-month after treatment, and the reoccurrence rate was monitored at 6 months after the treatment ended. Results The efficient for the treatment group and control group were 54.84% and 41.93%, respectively, after 3-month treatment, and there was no statistical significance between the two groups (P>0.05). However, after 6-month treatment, the efficient for the treatment group and control group were 77.42% and 51.61%, respectively, the difference between the two groups was statistically significant (P<0.05). Additionally, there were no adverse reactions for the patients in the two groups. The reoccurrence rates for the treatment group and control group at 6-month after treatment ended were 21.43% and 50%, respectively, the difference of reoccurrence rate has statistical significance (P<0.05). Conclusion The long-term treatment efficacy of CO₂ laser combined with Debaosong packet is superior to that of the combination of plum blossom needle with external application of Debaosong. The reoccurrence rate is lower and the treatment safety is guaranteed.