奶牛酒精阳性乳与自由基代谢及乳腺损伤关系的研究

对酒精阳性乳患牛衄清与乳清中的抗氧化指标进行了检测，从自由基代谢与损伤的角度探讨了酒精阳性乳的发病机理；同时检测了阳性牛血清与全乳中微量元素Zn、Cu、Mn、Fe的含量，分析了微量元素含量变化与自由基代谢的关系。试验结果显示阳性牛体内发生了过度的过氧化反应，机体总抗氧化能力下降，机体的扰氧化系统已不能有效地清除活性氧及代谢产物，过多的氧自由基可能对乳腺上皮分泌细胞细胞膜造成微损伤，从而引起乳腺细胞分泌异常乳。

Relationship between Alcohol Positive Milk and the Metabolism of Free Radicals, the Injury of Mammary Gland in Dairy Cows

The anti-oxidative indexes in the serum and whey of the cow suffered from alcohol positive milk(APM) were detected.And the mechanism of APM was probed from the free radicals/ disorder in this test.Meanwhile,concentrations of microelement Zn,Cu,Mn,Fe in the serum and milk were detected and the relationship between concentrations of microelement and the free radicals/ metabolism was investigated.According to the result of experiment,excessive anti-oxidative reaction occurs and the total anti-oxidation capability goes down in the cow with APM.The system of anti-oxidation in the body can not eliminate the active oxygen and metabolites effectively,maybe the epithelial cells of mammary gland were mini-injured by the surplus of free radicals.It leads to the occurrence of alcohol positive milk.