钩腺大戟根的化学成分研究

目的]研究大戟科大戟属植物钩腺犬戟（Euphorbia sieboldiana MerrelDecme．）根的化学成分。方法]采用硅胶柱层析、葡聚糖凝胶柱层析等色谱技术分离化合物，并通过理化性质和波谱特征鉴定其结构。结果]从钩腺大戟根的石油醚提取物中分离得到6个化合物，分别为良香树脂醇乙酸酯（β-amyrin acetate I）、2，4-二羟基16-甲氧基-3-醛基-苯乙酮（2，4-dihydroxy-5-methoxy-3-alde-hydoacetophenone，Ⅱ、1-（2，4二羟基-6-甲氧基-3-甲基）-苯乙酮1-（2，4-dihydroxy-6-methoxy-3-methylphenyl）ethanone，Ⅲ]、3-甲氧基4羟基-反式苯丙烯酸正十八醇酯（octadecanyl-3-methoxy-4-hydroxy-benzeneacrylate Ⅳ）、阻谷甾醇（β-sitosterol，V）、二十八烷醇（1-octacosanol，Ⅵ）。结论]所分得的6个化合物均为首坎从该植物申分离得到．

Study on the Chemical Constituents in the Roots of Euphorbia sieboldiana

Objective] The research aimed to study the chemical constituents in the roots of Euphorbia sieboldiana Merr et Decme.Method] The chemical constituents were isolated by column chromatography including silica gel and Sephadex LH20,and their structures were identified by physicochemical and spectral characterisitcs.Result] Six compounds were isolated from the petroleum benzine extract and the compounds were identified as β-amyrin acetate(I),2,4-dihydroxy-6-methoxy-3-alde-hydoacetophenone(II),1-(2,4-dihydroxy-6-methoxy-3-methylphenyl)ethanone(III),octadecanyl-3-methoxy-4-hydroxy-benzeneacrylate(IV),β-sitosterol(V),1-octacosanol(VI).Conclusion] The six compounds were isolated from Euphorbia sieboldiana for the first time.