抗菌中药及复方对嗜水气单胞菌的体外抑制效果

目的]评价中药对嗜水气单胞菌的体外抑菌效果。方法]取五倍子、大黄、鱼腥草等30种中药，采用水提法制备药液，通过试管二倍稀释法测定各药液对嗜水气单胞菌的最小抑菌浓度（MIC）及最小杀菌浓度（MBC），筛选出抗菌作用较强的中药作为主药，与牡丹皮、龙胆草、蒲公英等18种中药组成复方，测定中药复方时嗜水气单胞菌的体外抑制效果。结果]五倍子、诃子、夏枯草、花椒对嗜水气单胞菌有较强的抑菌活性（MIC≤6．25mg／ml），选取7种主药与清热凉血、清热燥湿、清热解毒药分别组成复方，其中五倍子、诃子与其他多种中药组成的复方抗菌作用增强；而花椒、五味子、乌梅与其他药物组成复方后，均出现抗菌能力不变或降低的现象。结论]诃子、五倍子等与清热燥湿药、清热凉血药、清热解毒药之间有协同作用，在实践中有较大的应用价值。

Effect of Chinese Herb Medicine and Antimicrobial Compound on the Inhibitory in vitro of Aeromonas hydrophila Strain

Objective]The inhibitory effect in vitro of traditional Chinese medicine on Aeromonas hydrophila bacteria was evaluated.Method] The solutions from 30 species of Chinese medicines such as gallnut,rhubarb and houttuyine encoeur were prepared with water extraction method,respectively.The minimal inhibitory concentration(MIC) and the minimum bactericidal concentration(MBC) of each solution to the strain were tested with the test - tube double dilution method.The traditional Chinese medicine with strong antiba...