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IMC10200株ALV-J实验诱发禽骨髓性白血病的研究
引用本文:顾玉芳,杨玉莹,赵振华,王金铃. IMC10200株ALV-J实验诱发禽骨髓性白血病的研究[J]. 中国预防兽医学报, 2004, 26(4): 278-281
作者姓名:顾玉芳  杨玉莹  赵振华  王金铃
作者单位:1. 内蒙古农业大学,动物科学与医学学院,内蒙古,呼和浩特,010018
2. 内蒙古畜牧科学院,动物医学研究所,内蒙古,呼和浩特,010030
摘    要:
对分离自肉种鸡群亚临床感染的J亚群禽白血病病毒IMC1o200株进行了实验感染诱发禽骨髓性白血病的病理学研究.IMC10200株J亚群禽白血病病毒尿囊腔接种11日龄肉鸡胚和SPF蛋鸡胚,孵出后跟踪观察.9周龄时随机抽检感染鸡,感染肉鸡特异引物PCR检测全部为阳性;组织病理学观察感染鸡无明显病变.至21周龄时感染肉鸡出现第一例典型骨髓性白血病病例;感染SPF蛋鸡未见明显J亚群禽白血病相关病变.

关 键 词:J亚群禽白血病病毒  IMC10200株  实验性  骨髓性白血病
文章编号:1008-0589(2004)04-0278-05
修稿时间:2003-08-05

Pathological observation of myeloid leukosis experimentally induced with IMC10200 strain ALV-J
GU Yu-fang,YANG Yu-ying,ZHAO Zhen-hua,WANG Jin-lin. Pathological observation of myeloid leukosis experimentally induced with IMC10200 strain ALV-J[J]. Chinese Journal of Preventive Veterinary Medicine, 2004, 26(4): 278-281
Authors:GU Yu-fang  YANG Yu-ying  ZHAO Zhen-hua  WANG Jin-lin
Affiliation:GU Yu-fang~1,YANG Yu-ying~2,ZHAO Zhen-hua~1,WANG Jin-lin~1
Abstract:
The present study was undertaken to observe experimental myeloid leukosis induced with IMC_(10200) strain ALV-J which was isolated originally from a normal broiler breeder.Specific pathogen free (SPF) leghorn and commercial meat-type chickens were used.11-day-old chick embryos were inoculated with IMC_(10200) strain ALV-J,hatched and reared.When reared to 21 weeks of age, some of experimental birds were selected randomly for PCR diagnosis and pathological observation. All of virus-inoculated meat-type chickens chosen were positive in PCR of H5/H7 but no clear pathologic changes.The first case of ML occurred in meat-type chickens with 42 weeks of age.No tumors were present in SPF leghorns infected.
Keywords:avian leukosis virus subgroup J  IMC_(10200) strain  experimental  myeloid leucosis
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