| CFL2基因研究进展 |
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| 引用本文： | 宋慧娟,苏玉虹.CFL2基因研究进展[J].中国农学通报,2006,22(2):28-28. |
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| 作者姓名： | 宋慧娟 苏玉虹 |
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| 作者单位： | 锦州医学院辽宁省高校分子细胞生物学与新药开发重点实验室,锦州,121001 |
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| 基金项目： | 辽宁省科技厅博士启动基金（20021072）和辽宁省教育厅基金（2004F112）资助项目. |
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| 摘 要： | CFL2（Cofilin 2）基因是肌动蛋白结合蛋白cofilin家族的新成员，主要在哺乳动物的骨骼肌和心肌表达，被认为是肌肉组织肌动蛋白装配的调节器，对正常肌肉功能和肌肉再生起着重要的作用。目前未见对CFL2基因进行全面介绍的文章，因此拟对CFL2基因的表达、结构、蛋白功能及其与肌病相关性方面的研究进展作一综述。
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| 关 键 词： | CFL2基因 肌动蛋白结合蛋白 肌病 |
| 收稿时间： | 2005-10-17 |
| 修稿时间： | 2005-10-17 |
Advances in the Research of CFL2 Gene |
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| Song Huijuan,Su Yuhong.Advances in the Research of CFL2 Gene[J].Chinese Agricultural Science Bulletin,2006,22(2):28-28. |
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| Authors: | Song Huijuan Su Yuhong |
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| Institution: | High Educational Key Laboratory of Molecular Cell Biology and Drug Research of Liaoning, Jinzhou Medical College, Jinzhou 121001 |
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| Abstract: | CFL2(Cofilin 2)is a new member of the cofilin family of actin-binding proteins, which is expressed predominantly in mammals skeletal muscle and heart. CFL2 is a regulator for actin assembly in muscle and may plays an important role in normal muscle function and muscle regeneration. The overall articles on theCFL2 gene are not been reported currently. This text makes an overview about the expression and the structure of CFL2gene, protein functions and its role in myopathies. |
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| Keywords: | CFL2 Actin-binding protein Myopathy |
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