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日本血吸虫病核酸疫苗的研究
引用本文:姚利晓,林矫矫. 日本血吸虫病核酸疫苗的研究[J]. 中国兽医寄生虫病, 2004, 12(4): 33-37
作者姓名:姚利晓  林矫矫
作者单位:中国农科院上海家畜寄生虫病研究所,上海,200232
摘    要:
核酸疫苗能同时诱发体液免疫和细胞免疫 ,具有众多传统疫苗无法比拟的优点 ,并且佐剂的应用能增强核酸疫苗的免疫效果。抗日本血吸虫核酸疫苗的研究在实验动物和牛、羊等大家畜上取得一定进展 ,混和或多价疫苗是未来核酸疫苗的发展方向

关 键 词:日本血吸虫  核酸疫苗
文章编号:1005-0868(2004)04-0033-05
修稿时间:2004-04-19

STUDY ON NUCLEIC ACID VACCINE OF SCHISTOSOMA JAPONICUM
YAO Li-xiao,LIN Jiao-Jiao. STUDY ON NUCLEIC ACID VACCINE OF SCHISTOSOMA JAPONICUM[J]. Chinese Journal of Veterinary Parasitology, 2004, 12(4): 33-37
Authors:YAO Li-xiao  LIN Jiao-Jiao
Abstract:
Both humoral and cellular immune responses can be induced by nucleic acid vaccine, which has more advantages than other traditional vaccine. Furthermore, the vaccine efficacy of protective immunity may be enhanced by adjuvants such as ISS, cellular factors and liposomes. Some achievements have been obtained about the vaccine against Schistosoma japonicum on mice and domestic animals, taking sheep and cow for examples. It's a direction to study on a mixed or cocktail nucleic acid vaccine.
Keywords:Schistosoma japonicum  nucleic acid vaccine
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