苦皮藤假种皮中的杀菌活性成分研究

用 5种溶剂对苦皮藤假种皮进行了系统提取 ,在灵敏的活性追踪指导下 ,从25%乙醇提取物中分离、鉴定了 3个具有杀菌活性的化合物 :麝香草酚、多羟基二氢沉香呋喃和间苯二酚 ,它们抑制玉米小斑病菌 Bip olaris maydis孢子萌发的 EC50 分别为 22 .27、53.32、169.29mg/L。其中麝香草酚为首次在卫矛科植物中分离得到 ,多羟基二氢沉香呋喃为首次在苦皮藤中分离得到。

Studies on Fungicidal Components of Celastrus angulatus

Chinese bittersweet(Celastrus angulatus Max.) is a traditional botanical insecticidal plant and distributes in most areas of China. More attentions are being paid to its insecticidal components, while little is known about its fungicidal constituents.Three fungicidal compounds were isolated from the fruit of Celastrus angulatus by the bioassay-guided isolation.Their structures were determined as 1α，2α，4β，6β，8α，9β，13-heptahydroxy-β-dihydroagarofuran(Ⅰ), resorcinol(Ⅱ) and thymol(Ⅲ) and their fungicidal activity (EC50)against Bipolaris maydis were 22.27,53.32 and 169.29 mg/L,respectively.