猪肺炎支原体体外抗菌药物敏感性试验研究

为了解猪肺炎支原体对抗菌药物的敏感性，采用宏量肉汤稀释法对4株猪肺炎支原体的最小抑菌浓度（MIC）值进行了测定。结果表明，猪肺炎支原体对泰妙菌素和环丙沙星最为敏感，MIC≤0．03μg／mL，其次分别为四环素类药物（包括四环素和多西环素）、林可霉素和泰乐菌素，而对氟苯尼考的敏感性则较差。本研究可为猪支原体肺炎的防控以及抗菌药物的合理使用提供参考。

Study on In vitro antimicrobial susceptibility detection of Mycoplasma hyopneumoniae

In order to investigate the antimicrobial susceptibility of Mycoplasma hyopneumoniae, broth macrodilution method was used to detect mininum inhibitory concentration （MIC） of four isolates in this study. Results showed that tiamulin and ciprofloxacin （ MIC ≤ 0.03 μg/mL） were the most susceptible to Mycoplasma pneumonia, followed by tetracyclines （tetracycline and doxycycline included）, lincomycin and tylosin. Reduced susceptibility to florfenicol of M. hyopneumoniae was observed. This study provides references for prevention and therapy of Mycoplasma pneumonia of swine and appropriate use of antimicrobial drugs.