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Two new cerebrosides from the pollen of Typha angustifolia
Authors:Wei-Wei Tao  Nian-Yun YangLi Liu  Jin-Ao DuanDe-Kang Wu  Da-Wei QianYu-Ping Tang
Affiliation:Jiangsu Key Laboratory for TCM Formulae Research, Nanjing University of Chinese Medicine, Nanjing 210046, China
Abstract:Two new cerebrosides, 1-O-(β-d-glucopyranosyloxy)-(2S,3S,4R,8Z)-2-[(2′R)-2′-hydroxytricosanoylamino]-8-nonadecene-3,4-diol (1) and 1-O-(β-d-glucopyranosyloxy)-(2S,3R,4E,8Z)-2-[(2′R)-2′-hydroxynonadecanoylamino]-4,13-nonadecene-3-diol (2), were isolated from the pollen of Typha angustifolia. Their structures were elucidated by chemical and spectral means. This is the first report on the occurrence of cerebroside in Typha (Typhaceae). Compounds 1 and 2 exhibited effect on the proliferation of cultured vascular smooth muscle cell (VSMCs) induced by fatal bovine serum (FBS).
Keywords:Typha angustifolia   Cerebroside   Vascular smooth muscle cell (VSMCs)
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