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A correlation network approach to metabolic data analysis for tomato fruits
Authors:Remco Ursem  Yury Tikunov  Arnaud Bovy  Ralph van Berloo  Fred van Eeuwijk
Institution:(1) Centre for BioSystems Genomics, P.O. Box 98, 6700 AB Wageningen, The Netherlands;(2) Laboratory of Plant Breeding, Wageningen University, P.O. Box 386, 6700 AJ Wageningen, The Netherlands;(3) Plant Research International, 6700 AA Wageningen, The Netherlands;(4) Biometris, P.O. Box 100, 6700 AC Wageningen, The Netherlands
Abstract:Network analysis of correlations between abundances of metabolites across tomato genotypes can help in unraveling the biological basis of organoleptic variation in tomato. We illustrate how to construct and interpret simple correlations networks using metabolic data collected on a diverse set of tomato genotypes. Various types of correlations are calculated and displayed in the form of networks. Interpretations on the basis of network analyses are compared to interpretations following principal components analysis.
Keywords:Correlation network  Metabolomics  Network analysis  Principal component analysis  Tomato
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