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柞蚕雄蛾浓缩液对肝细胞的保护和对高脂血症的治疗效果
引用本文:邹德庆,郑淑湘,阮怀军,于振诚,范作卿,张维东.柞蚕雄蛾浓缩液对肝细胞的保护和对高脂血症的治疗效果[J].蚕业科学,2006,32(4):532-536.
作者姓名:邹德庆  郑淑湘  阮怀军  于振诚  范作卿  张维东
作者单位:山东省蚕业研究所,烟台,264002;山东省医学科学院基础医学研究所,济南,250100
摘    要:为探讨柞蚕雄蛾浓缩液的保健和医用价值,分别就柞蚕雄蛾浓缩液对小鼠的保肝降酶作用和对半胱氨酸所致大鼠高脂血症的影响进行了实验。结果表明:该浓缩液可明显降低四氯化碳中毒小鼠血清中的谷丙转氨酶水平,因而能减少肝细胞变性、坏死的程度和范围,对受损伤的肝组织具有明显保护作用;可明显减轻肝组织脂肪样变性及降低由半胱氨酸所致高脂血症大鼠血清中的胆固醇、甘油三酯、低密度脂蛋白浓度,提高高密度脂蛋白浓度,因而对于高脂血症有良好的治疗效果。

关 键 词:柞蚕雄蛾浓缩液  动物实验  肝细胞  谷丙转氨酶  高脂血症
文章编号:0257-4799(2006)04-0530-05
修稿时间:2006年6月21日

The Protecting Effect on Liver Cell and Therapeutic Effects on Hyperlipoproteinemia of the Concentrated Extract of Tussah Male Moth
ZOU De-Qing,ZHENG Shu-Xiang,RUAN Huai-Jun,YU Zhen-Cheng,FAN Zuo-Qing,ZHANG Wei-Dong.The Protecting Effect on Liver Cell and Therapeutic Effects on Hyperlipoproteinemia of the Concentrated Extract of Tussah Male Moth[J].Acta Sericologica Sinica,2006,32(4):532-536.
Authors:ZOU De-Qing  ZHENG Shu-Xiang  RUAN Huai-Jun  YU Zhen-Cheng  FAN Zuo-Qing  ZHANG Wei-Dong
Abstract:In order to explore the hygienic and medical value of the concentrated extract of tussah male moth, the experiments about effect on protecting liver and reducing enzyme of mouse and on hyperlipoproteinemia of rat were carried out respectively.The results indicated:the concentrated extract can reduce the glutamate- pyruvate transaminase level in serum and the degree and range of denaturation and necrosis of liver cell to protect the destroyed liver tissue,and decrease the concentration of cholesterol,triglyceride and low density lipoprotein and increase the concentration of high density lipoprotein in serum of the rat,so it has better effect on hyperlipoproteinemia.
Keywords:Concentrated extract of tussah male moth  Animal experiment  Lliver cell  GPT  Hyperlipoproteinemia
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