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| 合成法氏囊素和LCGF与卵黄抗体对鸡IBD的治疗作用 | |
| 引用本文： | 王爱华,郭欣怡,靳亚平,司永嘉,吴庆侠.合成法氏囊素和LCGF与卵黄抗体对鸡IBD的治疗作用[J].动物医学进展,2001,22(1):72-74. |
| 作者姓名： | 王爱华 郭欣怡 靳亚平 司永嘉 吴庆侠 |
| 作者单位： | 1. 西北农林科技大学畜牧兽医学院, 2. 杨凌职业技术学院, 3. 西北农林科技大学畜牧兽医学院99届学生, |
| 基金项目： | 西北农林科技大学青年科研基金 |
| 摘 要： | 应用溶血空斑试验和溶血分光光度测定法分析了合成法氏囊素（BS）及其结构类似物－肝细胞生长因子（LCGF）对机体抗体形成细胞的影响，并进一步研究了二者对IBD的治疗作用。结果证明，合成BS和LCGF均能显著提高小鼠抗体形成细胞的增殖，促进小鼠抗SRBC抗体分泌（P＜0．01）。治疗试验表明，合成BS和LCGF或卵黄抗体单独应用，均可显著提高IBD发病鸡群的成活率（P＜0．01）。BS，LCGF单独应用或与卵黄抗体结合的治疗效果均显著高于试验剂量的卵黄抗体（P＜0．01），高剂量的BS能促进病鸡法氏囊损伤的修复。 |
| 关 键 词： | 法氏囊素 肝细胞生长因子 鸡 IBD 治疗 |
| 文章编号： | 1007-5038(2001)01-0072-03 |
| 修稿时间： | 2000年12月25 |
Treatment of chicken IBD with Synthetic bursin,LCGF and k Ant ibody |
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| WANG Ai-hua,GUO Xin-yi,JIN Ya-ping,SI Yong-jia,WU Qing-xia.Treatment of chicken IBD with Synthetic bursin,LCGF and k Ant ibody[J].Progress In Veterinary Medicine,2001,22(1):72-74. | |
| Authors: | WANG Ai-hua GUO Xin-yi JIN Ya-ping SI Yong-jia WU Qing-xia |
| Institution: | WANG Ai hua 1,GUO Xin yi 2,JIN Ya ping 1,SI Yong jia 1,WU Qing xia 1 |
| Abstract: | The effects of Bursin(BS) and its structural analog (liver cell growth factor, LCGF) , in vivo, on antibody secreting cells from mouse spleen were determined through Hemolytic Plaque Formation Tests and Spectrophotometric determination .Further , the therapeutic efficacy of the BS, LCGF and Yab(yolk antibody) to chicken IBD was investigated as well. The results testified that both BS and LCGF can enhance the number of PFCs and the amount of the anti SRBC antibody secreted by the spleen B cells in mouse (P<0.01). The therapy tests show that all the BS , LCGF and Yab can increase the survival rates of IBD chicken (P<0.01) and the rates of the chicken treated with BS , LCGF,BS+Yab and BS+Yab are higher than those treated with Yab alone(P<0.01).the BS at high dose can promote the rehabilitating of the Bursa of Fabricius damaged by IBDV. |
| Keywords: | bursin LCGF IBD therapy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |