| 板蓝根、黄芪对猪繁殖与呼吸综合征病毒的体外抑制作用 |
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| 引用本文： | 王学斌,魏战勇,崔保安,郭世栋,徐端红.板蓝根、黄芪对猪繁殖与呼吸综合征病毒的体外抑制作用[J].畜牧与兽医,2006,38(4):11-14. |
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| 作者姓名： | 王学斌 魏战勇 崔保安 郭世栋 徐端红 |
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| 作者单位： | 河南农业大学牧医工程学院,河南,郑州,450002 |
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| 基金项目： | 河南省重点科技攻关项目(0223033400) |
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| 摘 要： | 为了解中草药黄芪、板蓝根对病毒增殖的抑制作用,对黄芪、板蓝根及二者联合使用在Marc-145的单层细胞上对猪繁殖与呼吸综合征病毒(PRRSV)增殖的抑制作用进行了研究。结果表明,板蓝根能够显著抑制PRRSV体外增殖,对PRRSV的最小直接杀灭浓度为0.195 mg/mL,最小阻断浓度为0.097 mg/mL;黄芪对PRRSV增殖的抑制作用较弱。板蓝根、黄芪联合使用时对PRRSV的抑制作用显著增强,板蓝根对PRRSV的最小直接杀灭浓度降为0.097 mg/mL,最小阻断浓度降为0.049 mg/mL。
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| 关 键 词： | 板蓝根 黄芪 PRRSV |
| 文章编号： | 0529-5130（2006）04-0011-04 |
| 收稿时间： | 2005-07-23 |
| 修稿时间： | 2005-07-23 |
In vitro inhibition of porcine reproductive and respiratory syndrome virus by Radix isatidis and Astragalus |
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| WANG Xue-bin,WEI Zhan-yong,CUI Bao-an,GUO Shi-dong,XU Duan-hong.In vitro inhibition of porcine reproductive and respiratory syndrome virus by Radix isatidis and Astragalus[J].Animal Husbandry & Veterinary Medicine,2006,38(4):11-14. |
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| Authors: | WANG Xue-bin WEI Zhan-yong CUI Bao-an GUO Shi-dong XU Duan-hong |
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| Institution: | Engineering College of Animal and Veterinary Science, Henan Agricultural University, Zhengzhou 450002, China |
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| Abstract: | The anti-PRRSV(porcine reproductive and respiratory syndrome virus) activities of Radix isatidis and Astragalus were studied by testing the inhibition to cytopathogenic effect(CPE) in Marc-145 cells.The minmal inhibitory concentration(MIC) was determined directly and indirectly.The results showed that the anti-PRRSV activity of 1∶1 mixture of Radix isatidis and Astragalus was significantly higher than that of Radix isatidis or Astragalus alone. |
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| Keywords: | Radix isatidis Astragalus PRRSV |
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