香砂六君丸中铝含量测定方法研究

目的]探索用铬天青-UV比色法测定香砂六君丸中铝含量的方法。方法]对样品的前处理条件和显色条件进行方法学研究，采用铬天青—十六烷基三甲基溴化铵的UV法，试样用干法消化，盐酸溶液浸提，在pH 5.8～6.2的浓度范围内进行比色测定铝含量。结果]样品中的铁和铜在抗坏血酸还原剂的作用下与邻菲罗林形成络合物，不干扰该方法；铀、钍、钽、铍干扰较大，但一般植物样中存在极少，可不予考虑。氯根、硝酸根、硫酸根等不干扰测定。平均回收率为101.8%，RSD为2.5%。结论]该方法具有干扰少、操作方便、灵敏度较高的特点。适用于含铝10%以下的样品测定，可作为该制剂的定量分析方法。

Study on the Methods of Aluminium Assaying in Xiangsha Liujun Pills

Objective] To explore the methods of using chromazurine-UV col-orimetry to test aluminium concentration in Xiangsha Liujun Pills. Method] Through methodological study of the pre-treatment conditions and coloration conditions of samples, chromazurine -hexadecyl trimethyl-ammonium bromide （HTAB） UV method was adopted , and the samples were digested in dry pro-cess, extracted by using hydrochloric acid solution, and colorimetric assay of aluminium carried out at pH 5.8-6.2. Result] Fe and Cu in samples co-form complexes with Phenanthroline for the action of ascorbic acid reducing agents, so they will not influence this method;U, Th, Ta, and Be show more interventions, but rarely exist in common plant sam-ples, so can be neglected. Chlorin, ni-trate radical and sulfate radical have no impact on the assaying. The mean recov-ery rate is 101.8%, RSD 2.5%. Conclu-sion] The method is easy to operate, has high sensitivity and limited interventions, so it is suitable for samping assaying with aluminium concentration below 10%, and can be used for the quantita-tive analysis of Xiangsha Liujun Pills.