益生菌对肠道黏膜免疫的影响

益生菌作为一类以活菌为主的新型菌制剂,能在肠道内定殖,维护肠道菌群平衡,并刺激肠黏膜免疫组织,对肠道黏膜免疫有重要的影响。益生菌可直接作用于宿主的免疫系统,刺激胸腺、脾脏和法氏囊等免疫器官的发育,促进巨噬细胞活力或发挥佐剂作用,活化肠黏膜内相关淋巴组织,使免疫球蛋白A分泌增加,使免疫球蛋白A生物合成增加,提高消化道黏膜免疫功能。

Effects of Probiotics on Mucosal Immunity in Intestine

As a new kind of live bacterial preparation,probiotics can site in intestine,and protect the balance of bacteria,and stimulate mucosal immunity in intestine,and evoke the humoral and cellular immunities.Probiotics can directly act on the immune system,and stimulate the development of immune organs.The immune organs include thymus gland and spleen and bursa of fabricius.It can promote the vitality of macrophage,and exert the action of adjuvant,and activate gut mucosal associated lymphoid tissues,and increase the secretion of sIgA,raise the biosynthesis of sIgA,and enhance the immunologic function of digestive tract.