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Effect of malignant catarrhal fever virus infection on the immune response of rabbits to sheep red blood cells |
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| Authors: | FR Rurangirwa EZ Mushi |
| Institution: | K.A.R.I., Veterinary Research Department, P.O. Box 32, Kikuyu, Kenya |
| Abstract: | Rabbits infected with African Malignant catarrhal fever virus mounted a depressed antibody response to sheep red blood cells compared to the antibody response of uninfected rabbits. Immunodepression was observed in rabbits immunised 0, 3, 5, 7 and 10 days after infection. Antibody response was not depressed in the rabbits immunised 1 day after infection. Despite the depressed antibody response to SRBC, the rabbits died with rising virus neutralising antibody to the virus. The possible causes of the immunodepression are discussed. |
| Keywords: | Malignant catarrhal fever sheep red blood cells antibody response immunodepressionAuthor Keywords: Fièvre catarrhale maligne Globules rouges de mouton Réponse en anticorps Immunodépression |
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