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硫酸化酵母β-葡聚糖注射剂体内外抗菌活性及安全性研究
引用本文:孙英峰,池晶晶,王东,王英珍.硫酸化酵母β-葡聚糖注射剂体内外抗菌活性及安全性研究[J].中兽医医药杂志,2013,32(2):43-45.
作者姓名:孙英峰  池晶晶  王东  王英珍
作者单位:天津市畜牧兽医研究所,天津,300112
基金项目:天津市应用基础及前沿研究计划面上项目(12JCYBJC20100)
摘    要:对本实验室前期制备的兽用硫酸酯化酵母β-葡聚糖注射液进行安全性检验、体外抑菌和体内抗感染试验。结果表明,注射液体外对金黄色葡萄球菌有明显的抑制作用,但对溶血性链球菌、大肠埃希氏菌无抑制作用;体内抗感染作用显著,并具有较高安全性。

关 键 词:硫酸化酵母β-葡聚糖注射剂  抗菌活性  安全性

Antibacterial effect and safety assessment of sulfated yeast β-glucan injection
SUN Ying-feng , CHI Jing-jing , WANG Dong , WANG Ying-zhen.Antibacterial effect and safety assessment of sulfated yeast β-glucan injection[J].Journal of Traditional Chinese Veterinary Medicine,2013,32(2):43-45.
Authors:SUN Ying-feng  CHI Jing-jing  WANG Dong  WANG Ying-zhen
Institution:(Tianjin Research Institution of Animal Husbandry and Veterinary Medicine,Tianjin 300112,China)
Abstract:Sulfated yeast β-glucan injection pre-prepared in our laboratory was studied to evaluate its safety and antibacterial effect in vitro and in vivo.The results showed that the injection had significant antibacterial activity against Staphylococcus aureus,and had no significant effect against hemolytic Strepto-coccus and Escherichia coli in vitro;It showed an significant anti-inflammatory effect and high safety in vivo.
Keywords:sulfated yeast β-glucan injection  antibacterial effect  safety
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