| 肽聚糖对鲫鱼嗜水气单胞菌灭活疫苗免疫增强效果的研究 |
| |
| 引用本文： | 郭玉娟,陈学年.肽聚糖对鲫鱼嗜水气单胞菌灭活疫苗免疫增强效果的研究[J].中国兽医科技,2006,36(1):33-36. |
| |
| 作者姓名： | 郭玉娟 陈学年 |
| |
| 作者单位： | 肇庆学院水产科学研究所,广东肇庆526061 |
| |
| 摘 要： | 为了探讨肽聚糖在鱼类抗嗜水气单胞菌（Aeromonas hydrophila，AH）感染中的免疫佐剂作用，用添加A3a肽聚糖的饲料投喂接种F-AH疫苗的彭泽鲫（Carassius auratus var．pengze）；通过测定鲫白细胞吞噬活性、血清和体表黏液溶菌酶活性、抗体效价以及活菌攻毒后的免疫保护率，证明肽聚糖与F-AH疫苗联合使用，鲫体表黏液和血清溶菌酶活性、白细胞吞噬活性、抗体效价以及活菌攻毒后的免疫保护率均显著提高，表明A3a肽聚糖是F-AH疫苗的良好佐剂，能增强鱼类F-AH疫苗免疫应答。
|
| 关 键 词： | 嗜水气单胞菌 彭泽鲫 肽聚糖 |
| 文章编号： | 1673-4696（2006）01-0033-04 |
| 收稿时间： | 2005-07-04 |
Enhancement of A3a-peptidoglycan on immune effect of inactivated vaccine against Aeromonas h ydrophila |
| |
| GUO Yu-juan, CHEN Xue-nian.Enhancement of A3a-peptidoglycan on immune effect of inactivated vaccine against Aeromonas h ydrophila[J].Chinese Journal of Veterinary Science and Technology,2006,36(1):33-36. |
| |
| Authors: | GUO Yu-juan CHEN Xue-nian |
| |
| Abstract: | In order to study the immune adjuvant effect of A3a-peptidoglycan on fishes infected with Aeromonas hydrophila, Carassius auratus var. pengze was inoculated with formalin-inactivated A. hydrophila and fed with a diet supplemented with appropriate amount of A3a-peptidoglycan . Immunoenhancement action of A3a-peptidoglycan was observed by determining lysozyme activity, phagocytic activity, agglutinating antibody titer and immunological protection rate after challenge with live A. hydrophila. Results showed that A3a-peptidoglycan could be used as an ideal adjuvant, which enhances immune response of fishes to the vaccine. |
| |
| Keywords: | Aeromonas hydrophila Carassius auratus var pengze A3a-peptidoglycan |
| 本文献已被 维普 等数据库收录！ |
