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IL-2在自然感染兔脑炎原虫獭兔体内免疫作用的研究
引用本文:张柳平,段艳,潘耀谦.IL-2在自然感染兔脑炎原虫獭兔体内免疫作用的研究[J].动物医学进展,2004,25(1):115-116.
作者姓名:张柳平  段艳  潘耀谦
作者单位:解放军军需大学军事兽医系,吉林,长春,130062;解放军军需大学军事兽医系,吉林,长春,130062;解放军军需大学军事兽医系,吉林,长春,130062
基金项目:国家自然科学基金资助项目 (39970 5 6 6 )
摘    要:为观察 IL-2在自然感染兔脑炎原虫獭兔体内的免疫作用 ,用双抗体夹心 EL ISA试剂盒对 8只自然感染兔脑炎原虫的獭兔和 4只健康长耳白对照兔的血清及培养 3 d和 4d的脾和淋巴结的细胞培养上清中的 IL-2进行了检测。检测结果为病兔与对照兔 IL -2平均含量差异不显著 (P >0 .0 5) ,但病兔 IL -2平均含量高于对照兔。提示 IL -2对病兔产生了一定的免疫作用 ,但可能不扮演主要角色

关 键 词:自然感染  兔脑炎原虫病  IL-2  免疫作用
文章编号:1007-5038(2004)01-0115-02
修稿时间:2003年7月23日

Study of IL-2 Immunity about Otter Rabbits Naturally Infected with Encephalitozoon cuniculi
ZHANG Liu ping,DUAN Yan,PAN Yao qian.Study of IL-2 Immunity about Otter Rabbits Naturally Infected with Encephalitozoon cuniculi[J].Progress In Veterinary Medicine,2004,25(1):115-116.
Authors:ZHANG Liu ping  DUAN Yan  PAN Yao qian
Abstract:In order to observe immunity of otter rabbits which naturally infected with Encephalitozoon cuniculi ,8 sick otter rabbits and 4 long ears white rabbits were used in this experiment.Then IL 2 from serum and supernatant of spleen and lymph node cells which incubated 3 days and 4 days were tested with IL 2 ELISA Kit. The result showed that quantity of IL 2 from sick otter rabbits and control rabbits was not significant(P> 0.05 ),but the quantity of IL 2 from sick otter rabbits was slightly higher than that of control rabbits.This suggests that IL 2 has certain immunity to sick rabbits but doesn't play an important role in the protective immunity.
Keywords:naturally infection  encephalitozoonosis  IL  2  immunity
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