疏血通对慢性肺心病急性加重期患者的疗效观察

目的观察疏血通注射液对慢性肺心病急性加重期患者的疗效。方法将慢性肺心病急性加重期患者50例随机分为常规治疗组(25例)和疏血通治疗组(25例)。常规治疗组利用常规的综合治疗,疏血通治疗组在综合治疗的基础上加用疏血通治疗。入院时、治疗后第8天停止吸氧30min后均分别测动脉血气分析及血液流变学指标。结果常规治疗组疗效劣于疏血通治疗组(Hc=3.9100,P<0.05)。疏血通治疗组动脉血二氧化碳分压(PaCO2)、血液流变学指标和肺动脉平均压显著低于常规治疗组,动脉血氧分压(PaO2)高于常规治疗组,差异均有统计学意义(P<0.01)。结论疏血通可降低慢性肺心病急性加重期患者血流粘滞度及肺动脉高压,升高PaO2水平,降低PaCO2水平,提高治疗效果。

Effect of Shuxuetong on patients with acute exacerbation of chronic cardiopulmonary disease

Objective To observe the therapeutic effect of Shuxuetong injection on patients with acute exacerbation of chronic cardiopulmonary disease(CCPD).Methods Fifty cases of acute exacerbation of CCPD were randomly divided into two groups: routine group were treated with conventional therapy, while Shuxuetong group received shuxuetong and conventional therapy.The arterial blood gas analysis and hemorheology were detected on admission and on 8th day after treatment.Results The therapeutic effect in Shuxuetong group was superior to that in routine group(P<0.05).Compared with routine group,PaCO2,hemorheologi cal indexes and mean pulmonary arterial pressure(MPAP) decreased,and PaO2 increased in Shuxuetong group(P<0.01 or 0.05).Conclusion Shuxuetong injection can imporve the therapeutic efficacy by reducing the blood viscosity,pulmonary hypertension and PaCO2,and elevating PaO2 in acute exacerbation of CCPD.