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A retrospective analysis of the efficacy of Oncept vaccine for the adjunct treatment of canine oral malignant melanoma
Authors:J. M. Ottnod  R. C. Smedley  R. Walshaw  J. G. Hauptman  M. Kiupel  J. E. Obradovich
Affiliation:1. Medical Oncology, Animal Cancer and Imaging Center, , Canton, MI, USA;2. Diagnostic Center for Population and Animal Health, Michigan State University, College of Veterinary Medicine, , East Lansing, MI, USA
Abstract:
Oral malignant melanoma (OMM) in the dog is often locally aggressive with a high metastatic potential and there are few treatment options that have been demonstrated to improve outcome of this disease. The purpose of this study was to determine whether adjunctive treatment with the Oncept melanoma vaccine affected the outcome of dogs with OMM that had achieved loco‐regional cancer control. Medical records from 45 dogs that presented to the Animal Cancer and Imaging Center were reviewed, including 30 dogs with stage II and III disease. Dogs that received the vaccine did not achieve a greater progression‐free survival, disease‐free interval or median survival time than dogs that did not receive the vaccine.
Keywords:metastasis  oncology  pathology  small animal  small animal internal medicine  small/large animal
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