| 莪术油注射液的制备及体外抗PRRSV作用试验 |
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| 引用本文： | 徐端红,崔保安,王学兵,张红英,魏战勇,张爱芹,况玲. 莪术油注射液的制备及体外抗PRRSV作用试验[J]. 河南农业科学, 2010, 0(10) |
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| 作者姓名： | 徐端红 崔保安 王学兵 张红英 魏战勇 张爱芹 况玲 |
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| 作者单位： | 新疆农业大学,动物医学学院,新疆,乌鲁木齐,830052;河南农业大学,河南,郑州,450002;河南农业大学,河南,郑州,450002;河南省动物性食品安全重点实验室,河南,郑州,450002;新疆农业大学,动物医学学院,新疆,乌鲁木齐,830052 |
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| 基金项目： | 郑州市科技创新团队项目 |
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| 摘 要： | 为筛选抗猪繁殖与呼吸综合征病毒(PRRSV)的中药,制备了莪术油注射液,并以其为试验药物,同时以利巴韦林注射液作为对照药物,观察在体外细胞上对PRRSV的作用效果。结果表明,自最大安全浓度(质量浓度)作倍比稀释后,二者对PRRSV均具有一定的抑制、杀灭和阻断作用。其中,莪术油注射液对PRRSV的杀灭作用较为突出,利巴韦林注射液杀灭和抑制作用均较为显著。
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| 关 键 词： | 莪术油注射液 猪繁殖与呼吸综合征病毒 体外抗病毒作用 吐温-80 |
Preparation of Oleum Curcumae Aromaticae Oil Injection and Its In Vitro Effects on Anti-PRRSV |
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| XU Duan-hong,CUI Bao-an,WANG Xue-bing,ZHANG Hong-ying,WEI Zhan-yong,ZHANG Ai-qin,KUANG Ling. Preparation of Oleum Curcumae Aromaticae Oil Injection and Its In Vitro Effects on Anti-PRRSV[J]. Journal of Henan Agricultural Sciences, 2010, 0(10) |
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| Authors: | XU Duan-hong CUI Bao-an WANG Xue-bing ZHANG Hong-ying WEI Zhan-yong ZHANG Ai-qin KUANG Ling |
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| Abstract: | For the screening of medicines anti-porcine reproductive and spiratory syndrome virus(PRRSV),Oleum curcumae aromaticae oil injection was prepared as the investigational drug to observe its in vitro effect on PRRSV.For a negative control,ribavirin injection was used.The results showed that,since the maximum safe concentration to do multiple proportion dilute,they had a certain degree of inhibition,killing,and blocking effects on PRRSV.Among them,the killing effect of oleum curcumae aromaticae oil injection was more prominent and ribavirin injection had a significant effect on inhibitory action and killing. |
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| Keywords: | Oleum curcumae aromaticae oil injection PRRSV In vitro antiviral effect Tween-80 |
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