| 硝基苯对小鼠急性毒性试验的研究 |
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| 引用本文： | 邢厚娟,王海波,王敏,徐世文. 硝基苯对小鼠急性毒性试验的研究[J]. 东北农业大学学报, 2007, 38(3): 380-383 |
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| 作者姓名： | 邢厚娟 王海波 王敏 徐世文 |
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| 作者单位： | 东北农业大学动物医学院,哈尔滨,150030;东北农业大学动物医学院,哈尔滨,150030;东北农业大学动物医学院,哈尔滨,150030;东北农业大学动物医学院,哈尔滨,150030 |
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| 基金项目： | 黑龙江省教育厅科学技术研究项目 |
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| 摘 要： | 用Weil's表的平均移动法进行了NB对雌性小鼠和雄性小鼠LD_(50)的测定。以组间距(对数剂量差值)为d=0.2,测得NB对雄性小鼠经口服的LD_(50)为525.8962mg·kg~(-1)BW,95%可信限为417.7342～662.0640mg·kg~(-1)BW;以组间距(对数剂量差值)为d=0.0667,测得NB对雌性小鼠经口服的LD_(50)为771.9692mg·kg~(-1)BW,95%可信限为714.8254～833.6812mg·kg~(-1)BW。
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| 关 键 词： | 硝基苯 急性毒性 小鼠 LD50 |
| 文章编号： | 1005-9369（2007）03-0380-04 |
| 修稿时间： | 2006-03-31 |
Effect of NB on acute toxicity in mice |
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| XING Houjuan,WANG Haibo,WANG Min,XU Shiwen. Effect of NB on acute toxicity in mice[J]. Journal of Northeast Agricultural University, 2007, 38(3): 380-383 |
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| Authors: | XING Houjuan WANG Haibo WANG Min XU Shiwen |
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| Affiliation: | College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China |
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| Abstract: | Using the mean motion method of Weil's table to determine the LD_(50) of the female mouse and male mouse induced by NB.The group spacing (logarithm dosage difference) was d=0.2,and the oral LD_(50) of the male mouse induced by NB was 525.8962 mg·kg~(-1) BW,95% confidence limit was 417.7342-662.0640 mg·kg~(-1) BW; the group spacing (logarithm dosage difference) is d=0.0667,and the oral LD_(50) of the female mouse induced by NB was 771.9692 mg·kg~(-1) BW,95% confidence limit was 714.8254-833.6812 mg·kg~(-1) BW. |
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| Keywords: | LD50 |
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